Seven Copa Sudamericana knockout fixtures hit the card this week. Here are the best parlay combinations with live odds from DraftKings.
Copa Sudamericana Parlay Picks – May 5-7, 2025
Seven CONMEBOL Copa Sudamericana knockout stage matches are on the slate across Tuesday and Wednesday night, and the markets are wide open across the board. With several fixtures showing near-identical odds on all three outcomes, there is genuine value to be found for sharp parlay builders. Let's break down the best combinations.
Match Analysis
Deportivo Riestra vs Grêmio (Tue 05 May, 23:00 UTC)
This is as coin-flip as it gets - Riestra are priced at +180, Grêmio at +190, and the draw at +180 on DraftKings. That level spread across all three outcomes signals genuine uncertainty. Grêmio are a recognised Brazilian Serie A club with continental experience, and as slight road underdogs at +190 there is a case they are undervalued here. Playing in Argentina is always difficult, but Grêmio's squad depth gives them an edge in knockout football. Grêmio +190 (DraftKings) looks like the value leg in this fixture.
Montevideo City Torque vs Palestino (Wed 06 May, 23:00 UTC)
Torque are installed as solid home favourites at -120, while Palestino are the big outsiders at +310. The draw at +245 is compelling but risky for parlays. Torque have home advantage in Montevideo and are expected to control this tie. The -120 price is short for a parlay leg but manageable when stacking with bigger prices elsewhere. Torque -120 (DraftKings) anchors a parlay nicely as the "banker" leg.
Audax Italiano vs Vasco da Gama (Wed 06 May, 23:00 UTC)
Vasco da Gama are slight away favourites at +180 against Chilean side Audax Italiano (+140). Vasco's Brazilian pedigree and resources typically give them an edge in continental competition, but Audax at home in Santiago cannot be dismissed. The home side at +140 actually offers the better value here - Audax have shown resilience in Copa Sudamericana play and +140 for a home win looks generous. Audax Italiano +140 (DraftKings) is a solid value pick.
Barracas Central vs Olimpia Asunción (Thu 07 May, 01:00 UTC)
Another nearly even three-way market - Barracas at +170, Olimpia at +175, draw at +195. Olimpia Asunción are one of Paraguay's most storied clubs with extensive Copa Sudamericana and Copa Libertadores experience. At +175 on the road, Olimpia represent excellent value - their experience in knockout football is a real differentiator. Olimpia Asunción +175 (DraftKings) is flagged as a value bet.
Macará vs CA Tigre BA (Thu 07 May, 01:00 UTC)
The Ecuadorian hosts Macará face Argentine visitors CA Tigre, and again the market is almost perfectly split - Tigre at +175, Macará at +170, draw +190. Argentine clubs tend to travel well in South America and Tigre, despite being a mid-table Argentine side, carry inherent quality. This one is genuinely too close to call for parlay purposes - best left out of core combinations.
Botafogo vs Racing Club (Thu 07 May, 01:30 UTC)
This is the marquee fixture of the midweek slate. Botafogo at +110 are slight home favourites over Racing Club at +225, with the draw at +240. Botafogo, as reigning Copa Libertadores champions, have enormous continental experience and home advantage in Brazil. At +110 they are still great value given the quality differential. Botafogo +110 (DraftKings) is a strong anchor leg for any parlay.
Alianza Atlético vs América de Cali (Thu 07 May, 03:00 UTC)
América de Cali at +125 as away favourites against Peruvian side Alianza Atlético is an interesting line. The Colombian visitors have the better continental pedigree and +125 for an away win in a knockout tie is generous. América de Cali +125 (DraftKings) is worth including as a value leg.
Recommended Parlay Combinations
Parlay 1 - South American Heavyweights (3-Leg) | Combined Odds: +830
- Grêmio to win vs Deportivo Riestra - +190 (DraftKings)
- Botafogo to win vs Racing Club - +110 (DraftKings)
- América de Cali to win vs Alianza Atlético - +125 (DraftKings)
This parlay leans on the clubs with the strongest continental experience and squad depth. Grêmio away in Argentina at +190 is the value anchor, Botafogo at home as Libertadores champions is a near-banker at +110, and América de Cali are solid away favourites at +125. All three feel underpriced given their pedigree in Copa CONMEBOL competition. Combined odds land around +830 - excellent return for three reasonably confident legs.
Parlay 2 - Home Banker + Value Outsider (2-Leg) | Combined Odds: +192
- Montevideo City Torque to win vs Palestino - -120 (DraftKings)
- Olimpia Asunción to win vs Barracas Central - +175 (DraftKings)
Torque at -120 is the safest leg on the board - home advantage and heavy favouritism make this the banker. Pairing it with Olimpia Asunción at +175 - who carry the experience of one of South America's most decorated clubs - gives this two-leg parlay a combined price of approximately +192. Solid value for a low-risk double.
Parlay 3 - Value Hunter Special (3-Leg) | Combined Odds: +1050
- Olimpia Asunción to win vs Barracas Central - +175 (DraftKings)
- Grêmio to win vs Deportivo Riestra - +190 (DraftKings)
- Audax Italiano to win vs Vasco da Gama - +140 (DraftKings)
For the value hunters willing to take on more risk, this three-leg combination targets three "underdog or even" sides that the market appears to have underpriced. Olimpia's experience, Grêmio's squad quality, and Audax Italiano's home advantage in Santiago all point to these prices being generous. Combined odds come in around +1050 - a $10 bet returns over $115 if all three land. High risk, high reward, but grounded in logic.
Best Value Flags
- Grêmio +190 - Brazilian Serie A quality as road underdogs in Argentina is mispriced.
- Olimpia Asunción +175 - One of South America's most experienced knockout clubs at near-even money away from home.
- Botafogo +110 - Reigning Libertadores champions at home, almost too cheap.
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