Best Soccer Parlay Picks: Serie A, EPL & La Liga – Sep 18-19

Soccer Parlay Picks: Friday & Saturday Slate – September 18-19

We've got a tasty cross-league slate to work with this Friday and Saturday, spanning Serie A, the English Premier League, La Liga, and Liga MX. With some genuinely interesting price discrepancies across the books, there are real parlay opportunities here. Let's break down the key fixtures and build our best combinations.

Fixture Breakdown

Serie A: Monza vs Sassuolo – Friday, September 18

Monza host Sassuolo in what the market is treating as a tight, low-scoring affair. The total line sits at 2.5 goals, with the Under priced at -103 (Bally Bet) - that's essentially a coin flip on goals, which is sharp value. BTTS Yes is a heavy -141 (theScore Bet), suggesting the books expect both sides to find the net despite the low total expectation. Monza are available at a generous +210 (FanDuel) as home favourites by bookmaker standards - though the odds tell a different story and actually make Sassuolo a slight favourite at +135 (Bally Bet). The draw at +260 (theScore Bet) is worth a glance in accumulators.

English Premier League: Brentford vs Chelsea – Friday, September 18

Chelsea head to Brentford as away favourites at +140 (Courtside), with Brentford available at a chunky +185 (BetMGM). The BTTS market is screaming Yes here - priced at -213 (Caesars), which is an extraordinarily short price that tells you the books are near-certain both sides will score. With Chelsea's attacking firepower and Brentford's tendency to stay in games, this makes intuitive sense. The Over 3.5 at +115 (Bally Bet) stands out as a genuine value flag - positive odds on a four-goal game in a London derby where both teams are expected to score is worth noting.

La Liga: Espanyol vs Elche CF – Friday, September 18

Espanyol come in as solid home favourites at -118 (BetMGM), with Elche available at a big +360 (Bally Bet). The total here is essentially a pick'em at 2.5 goals, with the Over at -118 (Bally Bet) and Under at -110 (Bally Bet). A low-scoring Espanyol home win looks like the play.

English Premier League: Tottenham Hotspur vs Aston Villa – Saturday, September 19

This is one of the more intriguing fixtures of the weekend. Spurs are a slim +100 favourite (Bally Bet) at home against an Aston Villa side available at +265 (Bally Bet). That even-money home price for Tottenham looks generous given they're at home in a Premier League fixture. The draw at +270 (Courtside) and the BTTS No at +125 (Bally Bet) are both worth considering for accumulator purposes. Over 2.5 is -122 (Courtside), suggesting a goal-heavy game is expected.

Liga MX: Puebla vs Atlante FC & FC Juárez vs Tigres – Saturday, September 19

In Liga MX action, Puebla are narrow favourites at +110 (DraftKings) against Atlante. Over 2.5 is a strong favourite at -156 (betPARX) suggesting a high-scoring game expected. Meanwhile, Tigres are favoured at -130 (Fanatics) to beat FC Juárez away from home.

Value Flags

• Brentford vs Chelsea Over 3.5 (+115, Bally Bet) - Positive odds on a four-goal game where BTTS is -213? That's a significant market discrepancy worth exploiting.
• Tottenham Hotspur +100 (Bally Bet) - Even money for Spurs at home against Villa is generous. Home advantage in the Premier League is worth more than this price implies.
• Elche CF +360 (Bally Bet) - A long shot, but 3.6/1 for an away win in a La Liga fixture where the total is essentially a coin flip suggests some value if you want a longer shot in your parlay.

Recommended Parlay Combinations

Parlay 1 - The Cross-League Value Treble

Our top play combines three legs across Serie A, the English Premier League, and La Liga for a balanced, well-researched accumulator.

• Monza vs Sassuolo - Under 2.5 Goals (-103, Bally Bet) - Near coin-flip odds on a low-scoring Serie A match where the market is tight. Solid foundation leg.
• Espanyol 1X2 Home Win (-118, BetMGM) - Espanyol are solid home favourites against a struggling Elche side. This is the anchor of the parlay.
• Brentford vs Chelsea - Over 3.5 Goals (+115, Bally Bet) - The standout value leg. Positive odds on a game where BTTS is -213 suggests the market hasn't fully priced the goal potential into the totals market.

Combined Parlay Odds: Approximately +272

Parlay 2 - The Premier League Weekend Double

Focusing on both Friday and Saturday's English Premier League fixtures for a cleaner two-leg Premier League special.

• Chelsea Away Win (+140, Courtside) - Chelsea as slight away favourites at Brentford. The price is generous enough to anchor a double and the Blues have the quality to take points here.
• Tottenham Hotspur Home Win (+100, Bally Bet) - Even money for Spurs at home is simply too good to ignore. Home advantage plus Spurs' attacking options makes this the value pick of the weekend.

Combined Parlay Odds: Approximately +380

Parlay 3 - The Goals Accumulator

A three-leg goals-focused parlay targeting the over markets across Friday's fixtures.

• Brentford vs Chelsea - BTTS Yes (-213 best avoided as a standalone, but in a parlay the juice reduces) (Caesars) - Both teams scoring in this London fixture is about as close to a certainty as soccer betting gets.
• Tottenham Hotspur vs Aston Villa - Over 2.5 (-122, Courtside) - Both Spurs and Villa have goals in them. The market agrees with Over being the short-priced side.
• Puebla vs Atlante FC - Over 2.5 (-156, betPARX) - Liga MX fixtures at this price point usually deliver goals and the books agree this is the likely outcome.

Combined Parlay Odds: Approximately +210

Final Thoughts

The standout value this weekend is the Brentford vs Chelsea Over 3.5 at +115 (Bally Bet). When BTTS Yes is -213 but the four-goal total is still at positive odds, that's a genuine market inefficiency. Parlay 1 is our recommended combination - mixing leagues, mixing markets, and carrying real value in each leg rather than just stacking heavy favourites.

Responsible gambling note: Always bet within your means - parlays are high-risk, high-reward wagers and should represent only a small portion of your overall betting activity.