Saturday's soccer slate spans the English Premier League, La Liga, Serie A and more. Here are the best parlay combinations with top odds.
Saturday Soccer Parlay Picks - September 19, 2026
Saturday's soccer slate is absolutely stacked, with fixtures running across the English Premier League, La Liga, Serie A, Liga MX, and even an FA Cup tie to kick things off Friday evening. With this much action on the board, the parlay opportunities are rich - and we've done the legwork to identify three smart combinations worth your attention.
Key Match Analysis
Brighton and Hove Albion vs Arsenal - English Premier League
Arsenal travel to the Amex as heavy favourites at -141 (BetMGM), and rightfully so given their quality across the squad. Brighton, however, are no pushover at home and have historically made life difficult for the top sides. The Over 2.5 goals at -135 (BetMGM) is the play here - both sides like to press high and commit men forward, and Arsenal in particular tend to generate high shot volumes. BTTS Yes at -132 (Caesars) is also worth noting - Brighton have the attacking threat to trouble any backline.
AS Roma vs Inter Milan - Serie A
This is the headline Serie A clash of the weekend. Inter Milan arrive as away favourites at +155 (theScore Bet) - a price that looks genuinely generous for a side of their calibre. Roma at home carry threat at +167 (Caesars), and with both sides possessing attacking firepower, the big concern here is whether the goals flow. BTTS Yes is priced at a very short -189 (theScore Bet) - the market is clearly expecting goals from both ends, which drives our interest in the Inter Milan away moneyline at +155 as a standalone value leg.
Sevilla vs Barcelona - La Liga
Barcelona are enormous favourites here at -455 (BetMGM), making a straight moneyline unappealing for parlay purposes. However, the Over 3.5 goals at -137 (Bally Bet) is intriguing - Barcelona are capable of running riot on their day, and Sevilla have shown defensive vulnerability. The BTTS No at +120 (DraftKings) offers a contrarian angle if you believe Barcelona could keep a clean sheet while piling on the goals - worth flagging as a value option.
Venezia vs Lazio - Serie A
Lazio are slight away favourites at +100 (BetMGM) - essentially a coin flip in price terms, but Lazio's away form and squad depth give them a real edge over a newly-promoted Venezia side still finding their feet in Serie A. That +100 represents genuine value when you factor in the quality differential. Under 2.5 goals at -105 (BetMGM) is also a lean worth considering given Venezia's likely defensive setup.
Newcastle United vs Hull City - English Premier League (FA Cup)
Newcastle are comfortable favourites at -164 (Bally Bet), and with Hull City visiting St James' Park, the Magpies should be dominant. The Under 2.5 goals at +128 (Bally Bet) catches the eye as a potential value leg - Newcastle can be efficient rather than prolific in cup ties, and Hull will set up to frustrate.
Nottingham Forest vs Coventry City - English Premier League (FA Cup)
Forest are heavy favourites at -164 (BetMGM) at the City Ground. Coventry are a Championship side and will face a significant step up in quality. Forest's home record makes them a reliable favourite here. BTTS No at +102 (FanDuel) is a near-even-money value pick - Forest could easily keep a clean sheet against lower-division opposition, and that price is very fair.
Value Flag - Inter Milan at +155
The standout value pick on the board is Inter Milan away at AS Roma, priced +155 at theScore Bet. The implied probability on that line is around 39%, but Inter's squad depth and away record in big Serie A fixtures suggest the true probability is significantly higher. This is the kind of price you jump on when a top-four European side is available at plus-money.
Recommended Parlays
Parlay 1 - The Premier Value Double
- Arsenal to win at Brighton - away -141 (BetMGM)
- Inter Milan to win at AS Roma - away +155 (theScore Bet)
Two quality sides backed at prices that represent real value. Arsenal's away form has been strong, and Inter at plus-money against a Roma side that can be inconsistent at home is the kind of edge sharp bettors look for. Combined odds come in at approximately +188 - a solid return on two well-reasoned legs.
Parlay 2 - Goals Galore Treble
- Brighton vs Arsenal - Over 2.5 goals at -135 (BetMGM)
- Sevilla vs Barcelona - Over 3.5 goals at -137 (Bally Bet)
- Bologna vs Torino - Over 2.5 goals at -105 (Bally Bet)
Three fixtures that scream goals based on the attacking quality on show. Barcelona away at Sevilla has the hallmarks of a high-scoring affair, Arsenal tend to open games up, and the Bologna-Torino derby historically delivers action. Combined odds on this treble land around +215.
Parlay 3 - Mixed Market Saturday Special
- Lazio to win at Venezia - away +100 (BetMGM)
- Nottingham Forest vs Coventry City - BTTS No at +102 (FanDuel)
- Athletic Bilbao to win vs Alavés - home -149 (Fanatics)
This treble mixes a value moneyline, a BTTS market, and a reliable home favourite to deliver an appealing combined price. Lazio at even money is the anchor value leg. Forest keeping a clean sheet against Championship opposition is highly plausible, and Athletic Bilbao at home are formidable. Combined odds on this combination sit around +272.
Saturday's Best Bets Summary
- Value Pick: Inter Milan ML +155 (theScore Bet) - generous price for European elite
- Parlay 1: Arsenal ML + Inter Milan ML - approx +188
- Parlay 2: Over 2.5 Arsenal-Brighton + Over 3.5 Sevilla-Barca + Over 2.5 Bologna-Torino - approx +215
- Parlay 3: Lazio ML + Forest BTTS No + Athletic Bilbao ML - approx +272
Responsible gambling reminder: Always bet within your means - gambling should be fun, not a financial strategy.
