14 National Football League games hit Sunday's slate. We've identified the sharpest spread-based parlay combinations with best available odds.
Sunday's National Football League Parlay Picks - Week 2
It's a loaded Sunday in the National Football League with 14 games on the slate, kicking off at 1:00 PM ET through the Sunday Night Football showdown in Kansas City. With a full card to work with, there's plenty of value to mine in the spread markets. Here are our best parlay combinations for September 20.
Reading the Market: Key Observations
Before we dive in, a few market notes worth flagging:
- San Francisco 49ers -13.5 is the biggest spread on the board. The Niners are massive home favourites against a Miami Dolphins side dealing with the short turnaround and significant talent gap this early in the season. DraftKings is offering -105 on that line - a tick of value.
- Pittsburgh Steelers +5.5 at New England stands out as a potential value spot. The Steelers are priced at +205 on the moneyline at FanDuel, implying a real chance to win outright. Getting 5.5 points with a team capable of winning flat looks generous.
- Kansas City Chiefs -6.5 in prime time against the Colts looks like a market consensus number, but Caesars offering +6.5 at -103 for Indianapolis is the sharpest number for the underdog side.
- Green Bay Packers -3.5 at +100 (Fanatics) - getting even money on a favourite is a rare opportunity and represents genuine value. The implied probability sits around 50% on a team that could easily be priced -120 or steeper.
Parlay 1: The Prime-Time Power Play (+634 combined)
This three-legger leans on two of the stronger market favourites covering comfortable spreads, anchored by the marquee Sunday Night Football matchup.
- San Francisco 49ers -13.5 (-105, DraftKings) - The 49ers at home against a struggling Dolphins squad is one of the clearest mismatches of Week 2. Even accounting for any rust, San Francisco's roster depth and home advantage makes covering 13.5 a reasonable ask.
- Kansas City Chiefs -6.5 (-110, theScore Bet) - Patrick Mahomes at Arrowhead under the lights is about as reliable a betting anchor as the National Football League offers. The Colts are a rebuilding side and this number feels soft for a Chiefs team that routinely covers at home in prime time.
- Green Bay Packers -3.5 (+100, Fanatics) - Getting even money on the Packers as road favourites is the value flag of the card. Jordan Love's squad at +100 against a Jets side that has questions at quarterback represents excellent expected value. Grab this before the market corrects.
Parlay 1 Combined Odds: +634 - A $100 bet returns $734.
Parlay 2: The Underdog-Spread Value Double (+252 combined)
A tighter two-legger focusing on teams getting points in games where the market may be overreacting.
- Pittsburgh Steelers +5.5 (-109, Bally Bet) - The Patriots are a surprise home favourite here, but New England has enough question marks that 5.5 points feels like a cushion the Steelers don't need. Pittsburgh's defence is stout enough to keep this game competitive, and +205 on the moneyline at FanDuel tells you this isn't a blowout situation. The spread is where the value lives.
- Cincinnati Bengals +2.5 (-102, DraftKings) - Houston is a slight favourite at home, but this is one of the tightest lines on the board. At -102, the Bengals are getting a nearly free 2.5 points in what shapes up as a competitive AFC divisional-feel battle. Joe Burrow against a Texans secondary that has vulnerabilities is a dangerous underestimation.
Parlay 2 Combined Odds: +252 - A $100 bet returns $352. This is the safer, more conservative play for bettors who want two strong legs without overextending.
Parlay 3: The Totals and Spread Mix (+389 combined)
This three-legger mixes a totals pick with two spread calls for variety and solid combined upside.
- Philadelphia Eagles -7 (-109, Caesars) - The Titans are struggling offensively, and Philadelphia's defence should dominate the line of scrimmage. A 7-point spread against Tennessee feels manageable for an Eagles team with clear NFC aspirations. The total sitting at just 39.5 tells you oddsmakers expect a low-scoring affair - meaning the Eagles likely need to control the clock and field position to cover, which suits their identity.
- Tampa Bay Buccaneers -8 (-110, theScore Bet) - Cleveland brings offensive limitations into a tough road environment in Tampa. The Browns' offence has been one of the league's most challenged units, and Baker Mayfield returning to haunt his former team (in spirit at least) with a comfortable home win feels right. The -8 is a big number, but the talent gap supports it.
- Under 39.5 (-108, BetMGM) - Eagles vs Titans - Doubling down on the Eagles-Titans narrative. Both defences are respected units, Tennessee's offence is limited, and Philadelphia is likely to play ball-control football. A total this low with two defensive-minded teams points firmly toward the under.
Parlay 3 Combined Odds: +389 - A $100 bet returns $489.
Best Single-Game Value Flags
Not building a parlay? Here are the best standalone bets on Sunday's National Football League slate:
- Green Bay Packers -3.5 (+100, Fanatics) - Even money on a favourite. Best value on the board.
- Minnesota Vikings +4.5 (-108, Bally Bet) - The Bears have early-season buzz, but 4.5 points is generous against a Vikings team that competes hard in division games.
- Jacksonville Jaguars +2.5 (+105, Caesars) - Getting positive money on the underdog in a game with a 2.5-point line is rare and worth a look.
Sunday National Football League Parlay Summary
- Parlay 1: 49ers -13.5 / Chiefs -6.5 / Packers -3.5 - +634
- Parlay 2: Steelers +5.5 / Bengals +2.5 - +252
- Parlay 3: Eagles -7 / Buccaneers -8 / Eagles-Titans Under 39.5 - +389
Good luck on Sunday's action. As always, shop the lines and lock in your best prices early - these numbers will move as kickoff approaches.
Please gamble responsibly - set a budget before you bet and never wager more than you can afford to lose.
