MLS action is packed this weekend with 7 fixtures on tap. Here are the best parlay combos and value bets based on live FanDuel and DraftKings odds.
MLS Weekend Parlay Picks - April 25-26, 2026
Seven MLS fixtures are on the slate this weekend, and the odds board is loaded with opportunity. We've combed through the live lines at FanDuel and DraftKings to bring you the sharpest parlay combinations and a few value spots worth flagging. Let's get into it.
Weekend Fixture Breakdown & Best Available Odds
Toronto FC vs Atlanta United FC - Sat Apr 25, 18:00 UTC
FanDuel has Toronto FC as a narrow favorite at -109, with Atlanta United available at +300 and the draw at +280. Toronto at home is always a factor at BMO Field, and the -109 price on a home win is essentially a coin flip - that's workable for a parlay leg. Atlanta at +300 is an interesting flier for a moneyline upset, but we're leaning toward the Toronto win here as the more reliable leg.
CF Montreal vs New York City FC - Sat Apr 25, 19:30 UTC
This is the most balanced match on the slate. FanDuel prices Montreal at +180, NYCFC at +145, and the draw at +260. NYCFC at +145 stands out as a potential value spot - an implied probability of roughly 41% for a side that travels well and carries serious attacking quality. If you're building a parlay, NYCFC +145 is a leg worth including.
Minnesota United FC vs Los Angeles FC - Sat Apr 25, 21:45 UTC
Minnesota is a slight home favorite at +145 (FanDuel), with LAFC at +190 and the draw at +260. LAFC at +190 is worth a look - that's an implied probability of about 34.5%, and this is a team with enough quality to win on the road. However, Minnesota's home record in MLS has generally been solid at Allianz Field, so we'll respect the home advantage here.
FC Cincinnati vs New York Red Bulls - Sun Apr 26, 00:30 UTC
FanDuel has Cincinnati as a home favorite at -118, with the Red Bulls at a juicy +300 and the draw at +320. Cincinnati at home is a strong parlay anchor at -118. The Red Bulls at +300 is a value flag - implied at just 25%, but NYRB are a disciplined defensive team that can nick results on the road. Still, we're taking the Cincinnati home win for parlays.
Inter Miami CF vs New England Revolution - Sun Apr 26, 00:30 UTC
The biggest favorite on the entire slate. FanDuel has Inter Miami at -250, New England at +650, and the draw at a massive +425. Miami at -250 is a tough pill to swallow for straight bets due to the juice, but as a parlay anchor it helps build combined odds significantly. New England at +650 is genuinely generous - that's only a 13.3% implied probability, and while Miami are clearly the stronger side, +650 is a value flag for the brave.
Columbus Crew SC vs Philadelphia Union - Sun Apr 26, 00:30 UTC
Columbus are home favorites at -115 (FanDuel), with Philadelphia at +350 and the draw at +300. The Crew at -115 at home is another solid parlay leg. Philadelphia at +350 is a value flag - implied at just 22.2%, which feels slightly low for a Union side that is always organized and dangerous. Still, we're using the Columbus home win in our combinations.
D.C. United vs Orlando City SC - Sun Apr 26, 00:30 UTC
DraftKings has D.C. United as slight favorites at -108, with Orlando City at +320. The draw price was not listed. D.C. at -108 is nearly even money and represents solid value for a home side. We'll use this one carefully given the missing draw line context.
Recommended Parlay Combinations
Parlay 1 - The Home Chalk 3-Leg Combo
- Toronto FC to Win - -109 (FanDuel)
- FC Cincinnati to Win - -118 (FanDuel)
- Inter Miami CF to Win - -250 (FanDuel)
Three home favorites stacked together. Despite the heavy juice on Miami, combining these three legs produces combined odds of approximately +175 to +190 depending on the book's parlay calculator. It's a lower-risk combination designed for consistent returns on three sides expected to control their home games.
Parlay 2 - The Value Hunter 3-Leg Combo
- NYCFC to Win - +145 (FanDuel)
- Columbus Crew SC to Win - -115 (FanDuel)
- D.C. United to Win - -108 (DraftKings)
This combo mixes a genuine value underdog in NYCFC with two home chalk picks. Combined odds land in the range of approximately +350 to +380 - a very attractive number for a three-teamer where two of the three legs are near even money. NYCFC at +145 is the key value driver here and gives the parlay real upside.
Parlay 2 - The Long Shot Swing 2-Leg Combo
- NYCFC to Win - +145 (FanDuel)
- Minnesota United FC to Win - +145 (FanDuel)
A two-leg underdog/slight-favorite combo with real punch. Both sides are priced at +145, and combining them generates combined odds of approximately +530 to +550. If you believe road form is being underpriced at the Montreal venue and that LAFC's travel schedule is a drag, this two-legger offers excellent bang for your bet.
Top Value Flags This Weekend
- New England Revolution +650 (FanDuel) - Only 13.3% implied. Even in a losing effort Miami often concede late. Tiny-stake flier only.
- Philadelphia Union +350 (FanDuel) - 22.2% implied for a disciplined Union side on the road feels thin. Worth a small straight moneyline bet.
- Atlanta United +300 (FanDuel) - 25% implied at Toronto is not outrageous for a road game that could go either way at -109 for the home side.
Final Thoughts
This MLS weekend card offers a great mix of near-chalk home favorites and genuinely generous underdog prices. Our strongest recommended play is Parlay 2 - The Value Hunter combining NYCFC, Columbus, and D.C. United for roughly +360 combined. It blends a real value leg with two reliable home favorites. Always shop lines between FanDuel and DraftKings before placing - small differences in juice add up over a full parlay.
