Five Copa Sudamericana knockout stage fixtures hit the board Tuesday and Wednesday. Here are the best parlay combinations with live odds from DraftKings.
Copa Sudamericana Parlay Picks - Tuesday & Wednesday, May 19-20
The CONMEBOL Copa Sudamericana serves up five knockout stage fixtures across Tuesday night and Wednesday, and the DraftKings odds board is loaded with value. From a wide-open Montevideo City Torque vs Deportivo Riestra clash to Sao Paulo hosting Millonarios as heavy favourites, there are several angles worth exploiting in multi-leg parlays. Let's break down the best combinations.
Match-by-Match Analysis
Montevideo City Torque vs Deportivo Riestra (Tue 19 May, 23:00 UTC)
This is one of the most evenly priced fixtures on the slate. Torque open as slight favourites at +115 on DraftKings, while Riestra are available at a juicy +245. The draw sits at +210. Playing on home soil in Montevideo gives Torque a tangible edge in a knock-out environment where defensive solidity tends to dominate. The home side's familiarity with the Estadio Centenario surroundings and the partisan crowd factor makes the +115 price on Torque look reasonable, but it's Riestra's big price that catches the eye as a value leg for brave bettors. In tight Copa Sudamericana ties, draw insurance is always tempting, but we lean toward the home side getting the job done.
Audax Italiano vs Barracas Central (Tue 19 May, 23:00 UTC)
Audax Italiano are listed as home favourites at +135, with Barracas Central available at +190 and the draw at +220 on DraftKings. The Argentine visitors from Barracas Central will bring physicality and Copa experience, but Audax have the home advantage in Santiago. At +135, Audax represent modest value for a home favourite, but the +190 on Barracas Central is intriguing - Argentine clubs have historically travelled well in this competition. We'll note this as a potential value pick at +190 if you want to spice up a parlay.
Sao Paulo vs Millonarios (Wed 20 May, 01:30 UTC)
Sao Paulo are the biggest favourites on the board at -164 on DraftKings, hosting Colombian giants Millonarios. Playing at the Morumbi in Sao Paulo, the Brazilian side enjoy enormous home advantage in CONMEBOL competition. Millonarios have quality in their squad but making the long trip to face one of Brazil's most storied clubs in a knockout tie is a tall order. The +475 on Millonarios is eye-catching but reflects genuine risk. Sao Paulo at -164 is the closest thing to a banker on this slate - the price is short but the selection is trustworthy as a parlay anchor.
C.D. Cuenca vs Recoleta FC (Wed 20 May, 03:00 UTC)
C.D. Cuenca open as strong home favourites at -161 on DraftKings, with Recoleta FC available at +450. Cuenca, based in Ecuador, have the altitude advantage playing in the Andean city - a well-documented factor that consistently troubles visiting South American sides unfamiliar with playing at elevation. Recoleta are a Chilean side who will find the conditions challenging. The -161 price on Cuenca is justified and pairs nicely with Sao Paulo as a double-banker in parlays.
América de Cali vs CA Tigre BA (Wed 20 May, 03:00 UTC)
This is the most genuinely open fixture of the midweek slate. América de Cali are priced at an even +100 on DraftKings - essentially a coin flip with home advantage - while Argentine visitors CA Tigre BA are available at +270. The draw sits at +225. Argentine clubs in CONMEBOL competition deserve respect on the road, but América de Cali at home in a knockout fixture at effectively even money represents solid value. The +100 is one of the best-priced home favourites on the board and offers excellent parlay value relative to the implied probability.
Value Flags
- Deportivo Riestra +245 (DraftKings) - Implied probability of roughly 29%. If Riestra arrive in good form, this is overpriced for a knockout fixture against a Uruguayan side. A genuine value flag for risk-tolerant bettors.
- Barracas Central +190 (DraftKings) - Argentine clubs regularly punch above their weight in Copa Sudamericana road ties. The +190 implies around 35% - arguably too low for a quality Argentine opponent.
- América de Cali +100 (DraftKings) - Even money for a home favourite is always worth considering. This is the strongest value anchor on Wednesday's card.
Recommended Parlay Combinations
Parlay 1 - The Double Banker (2 Legs)
Anchor this parlay on the two strongest home favourites of the midweek slate and keep it clean.
- Sao Paulo to win (H2H Home) -164 - DraftKings
- C.D. Cuenca to win (H2H Home) -161 - DraftKings
Both sides enjoy significant home advantage - Sao Paulo at the Morumbi and Cuenca with their altitude edge. Combined odds land around +155, giving you a tidy return on two high-confidence selections. This is the safest parlay on the board this week.
Parlay 2 - The Value Accumulator (3 Legs)
Mix the two bankers above with an upset kicker to boost the payout significantly.
- Sao Paulo to win (H2H Home) -164 - DraftKings
- C.D. Cuenca to win (H2H Home) -161 - DraftKings
- América de Cali to win (H2H Home) +100 - DraftKings
América de Cali at even money is the standout value leg here. Combining three home sides across the knockout slate delivers combined odds of approximately +354. This is the parlay with the best risk-to-reward profile this week.
Parlay 3 - The Upset Special (3 Legs)
For bettors looking for bigger returns, this combination targets two genuine upsets alongside the safer Sao Paulo banker.
- Sao Paulo to win (H2H Home) -164 - DraftKings
- Barracas Central to win (H2H Away) +190 - DraftKings
- Deportivo Riestra to win (H2H Away) +245 - DraftKings
Barracas Central at +190 and Deportivo Riestra at +245 are both flagged for value above. Argentine clubs have a strong track record in Copa Sudamericana away ties, and pairing them with Sao Paulo as the anchor creates a high-upside ticket. Combined odds come in around +1085 - a long shot, but a well-reasoned one.
Quick-Fire Best Bets Summary
- Sao Paulo -164 (DraftKings) - Parlay anchor of the week
- C.D. Cuenca -161 (DraftKings) - Altitude advantage cannot be overlooked
- América de Cali +100 (DraftKings) - Best-value home favourite on the board
- Barracas Central +190 (DraftKings) - Argentine road value
- Deportivo Riestra +245 (DraftKings) - Value flag for upset hunters
Responsible gambling reminder: Parlays are high-risk wagers - always bet only what you can afford to lose and use deposit limits to stay in control.
