Two Serie A fixtures close out the season on Saturday. We break down the best parlay combinations with value picks across both games.
Serie A Saturday Parlay Picks - May 23, 2026
Serie A wraps up its final matchday on Saturday with two fixtures that offer some genuinely interesting betting angles. FC Internazionale Milano travel to Bologna needing a result to cement their title credentials, while SS Lazio host AC Pisa 1909 in what looks like a one-sided affair. Let's break down the best parlay combinations available.
Match Context
Bologna FC 1909 vs FC Internazionale Milano (17:00 UTC)
Inter Milan sit comfortably at the top of the Serie A table with 86 points from 37 games - a dominant campaign by any measure. Bologna find themselves in 8th place on 55 points, a solid mid-table finish, but they are a different proposition to the title-winning machine that Inter have been this season. Inter's goal difference of +54 dwarfs Bologna's +3, telling you everything you need to know about the quality gap here.
The market has Inter as moderate favourites at +120 (Bally Bet) for the away win, with Bologna at +210 (Caesars) and the draw at +310 (Fanatics). Given Inter's superiority, +120 on the away win looks like a genuine value opportunity - the implied probability sits around 45% which underestimates Inter's actual chances in this fixture on current form.
With Inter's relentless attacking quality, goals are expected. The BTTS YES at -200 (BetMGM) is far too short to use in parlays, but the market telling us both teams will likely score does support the Over 2.5 total at -179 (Bally Bet) - although that price makes it a standalone consideration rather than a parlay leg. Inter have conceded just 5 times in 37 games... wait, their GD of +54 suggests their attack is elite. Bologna will need to threaten on the counter if they're to get anything here.
SS Lazio vs AC Pisa 1909 (19:45 UTC)
This is as close to a banker as Serie A can offer on the final day. Lazio sit 9th on 51 points, a comfortable mid-table position with a neutral goal difference. Pisa, however, are rock bottom - 20th place, just 18 points from 37 games, a goal difference of -44, and just 2 wins all season. They are the worst team in the division by a significant margin.
Lazio at -175 (BetMGM) looks firmly justified given Pisa's catastrophic campaign. The Pisa away win at +510 (Bally Bet) is purely academic. More interesting is the totals market - Over 2.5 at -130 (Bally Bet) is attractive given Lazio's home form against a Pisa side that has shipped goals all season, and the BTTS NO at -110 (DraftKings) is worth a look given Pisa's inability to score consistently - just 2 wins in 37 games suggests a very low-output attack.
Value Flag: The draw price at +330 (Fanatics) for the Lazio-Pisa game is interesting if you believe Lazio could be flat on the final day, but given the gulf in quality, it's not a market we'd recommend chasing.
Recommended Parlay Combinations
Parlay 1 - The Quality Double (+265 approx)
Our headline parlay combines the two most logical outcomes across Saturday's slate:
- Inter Milan Away Win (+120, Bally Bet) - The champions-elect to dispatch Bologna on the road
- Lazio Home Win (-175, BetMGM) - Near-certainty against the league's bottom side
This combination pays around +265 for what we consider two well-supported outcomes. Inter's superiority in this standings comparison is stark, and Lazio hosting the division's worst team should be a routine three points.
Parlay 2 - Goals Parlay (+150 approx)
For those who like attacking angles, this two-legger targets goals in both games:
- Lazio vs Pisa Over 2.5 Goals (-130, Bally Bet) - Lazio's attack against a leaky Pisa defence should deliver
- Inter Milan Away Win (+120, Bally Bet) - The quality side to take all three points
Combined odds land around +150. Lazio have a goal difference of 0 on the season but hosting a Pisa side with -44 GD is a different challenge entirely - the goals should flow. Pairing that with Inter on the road gives this parlay solid foundations.
Parlay 3 - Three-Leg Value Builder (+480 approx)
For the bolder play, this three-legger adds a totals angle on the Bologna game:
- Lazio Home Win (-175, BetMGM)
- Inter Milan Away Win (+120, Bally Bet)
- Lazio vs Pisa BTTS No (-110, DraftKings) - Pisa's attack has been abysmal all season; backing them NOT to score in a hostile away fixture has merit
This pays roughly +480 and the BTTS No leg is our value flag of the day - Pisa averaging well under a goal per game away from home against a Lazio side that will be motivated to finish the season well. At -110, DraftKings are essentially calling it a coin flip - we strongly disagree.
Best Available Odds Summary
- Inter Milan Win: +120 - Bally Bet
- Lazio Win: -175 - BetMGM
- Lazio vs Pisa Over 2.5: -130 - Bally Bet
- Lazio vs Pisa BTTS No: -110 - DraftKings
- Bologna Draw: +310 - Fanatics (long-shot angle only)
All odds correct at time of writing. Always shop lines before placing.
Responsible gambling reminder: Betting should always be fun - set a budget before you play and never chase your losses.
