Four Serie A fixtures hit the slate this Saturday. Here are the best parlay combinations with value odds across Udinese, Inter Milan, Parma and Genoa.
Saturday Serie A Parlay Picks – 22 August 2026
Serie A is back, and Saturday's opening slate serves up four intriguing fixtures with some genuinely juicy odds across the board. With all clubs sitting at zero points on a fresh season slate, we're leaning on squad quality, market signals, and bookmaker pricing to find the best parlay value. Let's break it all down.
Match-by-Match Breakdown
Udinese vs Como – 17:30 UTC
Como were promoted back to Serie A and arrive as slight favourites according to the market at -118 (BetMGM), which is a little surprising for a road side at Udinese's Bluenergy Stadium. Udinese are priced as underdogs at +390 (FanDuel), reflecting Como's investment and squad depth since their return to the top flight. The total sits at 2.5 goals, with the under priced at -149 (Bally Bet) - suggesting bookmakers expect a tight, cagey opener. BTTS Yes is right on the money at +100 (DraftKings), which represents genuine value if both sides get off to an attacking start.
Inter Milan vs Monza – 17:30 UTC
This is the most lopsided fixture on the card. Inter Milan, reigning Serie A champions and European heavyweights, host Monza at -455 (BetMGM). Monza at +1400 (FanDuel) is lottery-ticket territory. The market is firmly expecting Inter to dominate, which is reflected in the Over 2.5 being priced at -164 (BetMGM) - short but logical given Inter's firepower. BTTS Yes at +152 (FanDuel) is a standout value flag - that's an implied probability of around 40%, which looks generous for a match where both sides could find the net even in a comfortable Inter win.
Parma vs Cagliari – 19:45 UTC
A real toss-up between two sides expected to fight near the bottom of the table this season. Parma at +163 (Bally Bet) as home side is attractive, while Cagliari at +200 (Fanatics) isn't far behind. The draw is priced at +220 (BetMGM), and honestly all three outcomes feel plausible. The total is firmly set under 2.5 at -189 (Bally Bet), a short price that underlines bookmaker confidence in a low-scoring battle. Over 2.5 at +143 (Bally Bet) looks like a sneaky value bet if either side finds early confidence.
Genoa vs Napoli – 19:45 UTC
Napoli, under new management and with a reshaped squad, are modest away favourites at -115 (Fanatics). Genoa at +400 (FanDuel) is a chunky home price and may attract some action. The total sits at 2.5, with the Over priced at +120 (BetMGM) - representing solid value in a match involving Napoli's attacking ambition. BTTS Yes at +105 (DraftKings) is another value flag - Genoa tend to score at home and Napoli's forwards should find opportunities too.
Recommended Parlay Combinations
Parlay 1 - The Quality Edge Double (+330 combined)
- Inter Milan to win (h2h) - No surprise here. Inter at -455 is steep alone, but it anchors a parlay nicely. FanDuel.
- Napoli to win (h2h) at -115 - Napoli have the quality to take three points at Genoa. Fanatics.
Combined odds: approximately +330. Two of the strongest squads on the card, both expected to win, and the parlay boosts the return significantly over flat betting either side.
Parlay 2 - Goals & Value Three-Legger (+480 combined)
- Inter Milan vs Monza - BTTS Yes at +152 - Exceptional value given Inter's tendency to allow the odd goal in comfortable wins. FanDuel.
- Genoa vs Napoli - Over 2.5 goals at +120 - Both teams capable of contributing to a three-goal game. BetMGM.
- Parma vs Cagliari - Draw at +220 - Two evenly matched sides with nothing to separate them on paper. BetMGM.
Combined odds: approximately +480. This three-legger mixes BTTS, a total, and a 1X2 across three different fixtures for excellent value and diversity.
Parlay 3 - Underdog Special (+650 combined)
- Udinese to win (h2h) at +390 - Home advantage matters in Serie A openers and Udinese know the Bluenergy crowd. FanDuel.
- Parma vs Cagliari - Over 2.5 goals at +143 - If both teams come out swinging in this relegation-flavoured contest, goals could flow. Bally Bet.
- Genoa vs Napoli - BTTS Yes at +105 - Genoa score regularly at home and Napoli will be hunting goals. DraftKings.
Combined odds: approximately +650. A higher-risk combination built around Udinese upsetting Como and some goal action in the later fixtures. Not for the faint-hearted, but the return justifies the stake allocation.
Best Value Flags This Saturday
- Inter Milan vs Monza - BTTS Yes at +152 (FanDuel) - Implied probability of ~40% looks too generous. Inter score freely and Monza often find a consolation.
- Genoa vs Napoli - BTTS Yes at +105 (DraftKings) - Nearly even money for both teams to score is strong value in a match with attacking quality on both sides.
- Parma vs Cagliari - Over 2.5 at +143 (Bally Bet) - The market leans under heavily but if Parma and Cagliari trade blows, this price will look very attractive.
Always gamble responsibly - set a budget before you bet and never chase losses.
