Premier League Gameweek 7 Predicted Lineups: Leeds United vs Manchester United

Gameweek 7 of the 2026/27 Premier League season is packed with compelling storylines, starting with the return of the Yorkshire derby as Leeds United host Manchester United at Elland Road. Both clubs head into the clash carrying doubt over key personnel, with Luke Shaw and Kobbie Mainoo listed as questionable for the visitors, adding real uncertainty to the selection picture before a ball is kicked.

Elsewhere, Liverpool travel to Brentford shorthanded in a big way, with Dominik Szoboszlai suspended and a lengthy injury list that includes Cody Gakpo, Alexander Isak and Conor Bradley among the outs. Arsenal visit Nottingham Forest as favourites but must do without William Saliba, while the Manchester City machine rolls on against Ipswich with no fresh injury concerns reported. Plenty of angles for bettors to work with across Saturday and Sunday.

Everton vs Chelsea - Saturday, 7:30 AM ET

Predicted Lineup Gameweek 7

Everton: Pickford; Branthwaite, Keane, Tarkowski, Maitland-Niles; Garner, Armstrong; Grealish, Dewsbury-Hall, Johnson; Barry
Chelsea: Martinez; Lacroix, Acheampong, Colwill; Chavarria, Caicedo, Henderson, Neto; Palmer, Rogers; Joao Pedro

Everton are predicted to be without left back Vitaliy Mykolenko, who is listed as doubtful, though the back four otherwise appears settled with Branthwaite and Tarkowski anchoring the centre. Chelsea have a few concerns of their own: Reece James is questionable, Jordan Gittens is ruled out, and Emmanuel Emegha is also doubtful up front. Cole Palmer slots in behind Joao Pedro in what looks like a dangerous attacking unit despite the absences.

For bettors, Chelsea are the road favourites here. With Palmer pulling the strings and Everton missing defensive cover at left back, both teams to score and Chelsea on the moneyline have appeal. Joao Pedro is worth noting as an anytime goalscorer, while Everton's home crowd gives them enough to at least threaten. Totals bettors should consider whether Everton's defensive solidity without Mykolenko tips the match toward the over.

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Brentford vs Liverpool - Saturday, 10:00 AM ET

Predicted Lineup Gameweek 7

Brentford: Kelleher; Diouf, van den Berg, Ajer, Kayode; Yarmolyuk, Janelt; Lewis-Potter, Jensen, Anthony; Thiago
Liverpool: Alisson; Kerkez, van Dijk, Jacquet, Araujo; Mac Allister; Barcola, Wirtz, Munoz; Koumas

This is one of the most fascinating team news stories of the weekend. Liverpool head to the Gtech Community Stadium without Szoboszlai, who is suspended, alongside a long list of outs including Gakpo, Isak, Ekitike, Bradley and others. Brentford are also carrying multiple doubts, with Nathan Collins, Mikkel Damsgaard, Josh Dasilva, Aaron Milambo, Kevin Schade and Joel Schuster all questionable. Kaye Furo is confirmed out.

Liverpool's depleted attack is a real concern for bettors considering them on the moneyline. Brentford at home with Igor Thiago leading the line could catch a patchwork visiting side off guard. The under is worth considering given Liverpool's attacking depth issues, though Wirtz and Barcola still offer quality on the flanks. Brentford plus goals in a draw could be a smart parlay component at bigger odds. Liverpool's backline looks capable even if the attack is thin.

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Fulham vs Hull City - Saturday, 10:00 AM ET

Predicted Lineup Gameweek 7

Fulham: Leno; Sessegnon, Bassey, Affengruber, Castagne; Berge, Charles; Iwobi, King, Bobb; Garcia
Hull City: Tzolakis; Giles, Ajayi, Egan, Mendy, Coyle; Thomas, Slater, Crooks, Belloumi; McBurnie

Fulham have two doubts to monitor: Tom Cairney in midfield and left back Antonee Robinson, who is listed as questionable. If Robinson misses out, Ryan Sessegnon steps in on that side. Hull arrive at Craven Cottage with a significant injury list, including Jack Butland, Darko Gyabi, Ilyas Ansah, Cameron Hughes, Eliot Matazo and Matt Targett all ruled out, with Cho Min-gi and Leo Gourna-Douath doubtful.

Fulham are comfortable favourites here and the absence of so many Hull players makes it hard to back the visitors. Gonzalo Garcia leads the Fulham attack and Oscar Bobb adds creativity from wide, making Fulham to win and over goals a reasonable parlay option. Hull's defensive shape with a five-man backline could limit the damage, but their depleted midfield makes it difficult to build sustained attacks. Anytime scorer markets for Fulham's front line deserve attention.

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Manchester City vs Ipswich Town - Saturday, 10:00 AM ET

Predicted Lineup Gameweek 7

Manchester City: Donnarumma; O'Reilly, Dias, Guehi, Nunes; Fernandez, Anderson; Semenyo, Cherki, Ndiaye; Haaland
Ipswich Town: Walton; Davis, O'Shea, Diop, Ouattara; Lukic, Palacios; Philogene, Enciso, Fatawu; Emersonn

Manchester City report no injuries heading into this one, a rare luxury that gives Pep Guardiola a full hand to play with. Rayan Cherki supports Erling Haaland through the middle in what looks like a potent attacking setup. Ipswich have midfielder Jack Taylor listed as questionable, but otherwise they name a full predicted XI. The visitors are significant underdogs and this is a tough venue to pick up points.

The heavy moneyline price on City reflects how strongly favoured they are, making them more useful in a parlay than as a standalone bet. Haaland remains the standout anytime goalscorer option in the Premier League, and this matchup looks like a prime opportunity. The over on total goals is appealing given City's firepower and Ipswich's attacking intent through Philogene and Fatawu. Clean sheet markets for City are also worth exploring given their defensive stability.

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Newcastle United vs Aston Villa - Saturday, 12:30 PM ET

Predicted Lineup Gameweek 7

Newcastle United: Hornicek; Hall, Thiaw, Botman, Dedic; Gonzalez, Miley; Barnes, Wissa, Murphy; Fernandez-Pardo
Aston Villa: Suzuki; Wan-Bissaka, Lindelof, Mings, Cash; Kamara, Gomes; Manzambi, Buendia, McGinn; Jackson

Newcastle have Valentino Livramento listed as questionable, while Jacob Ramsey and Bertrand Traore are doubts and Allan Elanga is confirmed out. Yoane Wissa is predicted to feature in an advanced midfield role behind the striker. Villa are without several key men including Ian Maatsen, Amadou Onana and Matty Cisse, all confirmed out, which thins their options considerably on the left and in midfield.

This is a closely matched fixture according to the odds, and the team news suggests both sides are carrying some uncertainty. Wissa has shown an eye for goal and could be a value anytime scorer pick for Newcastle. Villa's Nicolas Jackson leads the line and will look to exploit whatever space Newcastle give. Both teams to score looks a reasonable angle given the attacking talent on both sides, and the match total could land around the lower end of the range with both defences capable of competing.

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Bournemouth vs Sunderland - Sunday, 9:00 AM ET

Predicted Lineup Gameweek 7

Bournemouth: Petrovic; Truffert, Hill, Silva, Smith; Adams, Christie; Gannon Doak, Tavernier, Rayan; Evanilson
Sunderland: Roefs; Reinildo, Danso, Mukiele, Hume; Sadiki, Xhaka; Angulo, Le Fee, Fofana; Isidor

Bournemouth have Amine Adli and Justin Kluivert listed as doubtful, a meaningful concern given both are attacking contributors. Jaidon Anthony Araujo and Emmanuel Kroupi are ruled out. Sunderland come in with a cluster of doubts of their own: Wahbi Isidor, Brian Brobbey, Habib Diarra and Thomas Meunier are all questionable, with Isidor appearing in the predicted XI despite that flag. Danny Ballard and Romain Mundle are confirmed out.

This is a genuinely competitive fixture on paper. Evanilson is the standout goalscorer angle for Bournemouth at home. Granit Xhaka gives Sunderland experience and control in the midfield pivot, and Enzo Le Fee adds creativity in the number ten role. With both clubs missing attacking options, the under on total goals could have value. Bournemouth on the moneyline at around even odds represents a solid parlay piece given home advantage and a slightly clearer attacking lineup.

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Brighton and Hove Albion vs Crystal Palace - Sunday, 9:00 AM ET

Predicted Lineup Gameweek 7

Brighton and Hove Albion: Verbruggen; Boscagli, Dunk, Vuskovic, Kadioglu; Gross, Chema; De Cuyper, Ayari, Gomez; Kostoulas
Crystal Palace: Benitez; Lerma, Richards, Canvot; Mitchell, Timber, Wharton, Khalaili; Pino, Kamada; Strand Larsen

Brighton have a significant number of doubts in attacking and wide areas: Joao Pedro Hinshelwood, Yankuba Minteh, Kaoru Mitoma, Pascal Struijk, Mats Wieffer and Zak Yohanna are all questionable. Evan Ferguson, Sverre Tzimas and Femi Azeez are out. Crystal Palace are without Axel Disasi through suspension and Chadi Riad is confirmed injured. Daichi Kamada and Yeremy Pino carry the creative load, while Joel Strand Larsen leads the line.

Brighton are heavy favourites in this south coast derby, but the sheer number of doubts in their squad introduces risk. Crystal Palace's defensive setup with a back three could make it a tighter game than the odds imply. The 21 mph winds forecast could affect the quality of play and keep the score down. Bettors might find value in the draw or a Palace upset at longer odds. Strand Larsen as an anytime scorer for the visitors is worth including in longer-shot parlay legs.

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Leeds United vs Manchester United - Sunday, 9:00 AM ET

Predicted Lineup Gameweek 7

Leeds United: Trafford; Elvedi, Justin, Muharemovic; Gudmundsson, Ampadu, Tanaka, Bogle; Okafor, Stach; Calvert-Lewin
Manchester United: Lammens; Shaw, Maguire, Martinez, Dalot; Tielemans, Mainoo; Cunha, Fernandes, Diallo; Mbeumo

This is the headliner of the weekend. Leeds have Daniel James listed as questionable on the wing, while Mateo Joseph and Joe Rodon are confirmed out. Manchester United carry doubts over Luke Shaw and Kobbie Mainoo, both of whom appear in the predicted lineup despite their questionable status. Patrick Dorgu, Benjamin Sesko and Manuel Ugarte are confirmed absentees, and both Karl Darlow and Tom Heaton are also listed as doubtful at goalkeeper.

The Elland Road atmosphere adds an unpredictable element, and Leeds at plus odds on the moneyline is an intriguing parlay inclusion. Dominic Calvert-Lewin leads Leeds and has Premier League pedigree, making him a value anytime scorer pick. Bryan Mbeumo and Bruno Fernandes give United quality, but missing Mainoo in midfield could hurt their balance. Both teams to score is a popular angle for derbies like this, and the emotional nature of the fixture could push the total higher.

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Nottingham Forest vs Arsenal - Sunday, 11:30 AM ET

Predicted Lineup Gameweek 7

Nottingham Forest: Sels; Cunha, Diomande, Murillo; Williams, Schlager, McAtee, Munoz; Gibbs-White, Ndoye; Delap
Arsenal: Raya; Calafiori, Konsa, Gabriel, White; Rice, Lewis-Skelly; Eze, Odegaard, Saka; Havertz

Nottingham Forest have doubts at centre back with Nikola Milenkovic and Nicolas Savona both questionable, and Igor Jesus is confirmed out up front, leaving Liam Delap to lead the line. Arsenal are without William Saliba, a major absence at the heart of their defence, with Ezri Konsa stepping in alongside Gabriel. Piero Hincapie is also out, and Christos Tzolis is ruled out. Martin Zubimendi is doubtful, though he does not appear in the predicted eleven.

Arsenal are favoured but Saliba's absence is significant and Forest at home are always a difficult proposition. The City Ground is a hostile environment and Gibbs-White and Delap will look to press Arsenal's reshuffled back line. Havertz leads the line for Arsenal with Saka and Eze providing width, keeping their anytime scorer options strong. The under could be interesting given both defences have injury concerns, but Arsenal's overall quality makes them a solid moneyline pick for parlay builders despite the defensive reshuffle.

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Tottenham Hotspur vs Coventry City - Monday, 3:00 PM ET

Predicted Lineup Gameweek 7

Tottenham Hotspur: Kinsky; Udogie, van Hecke, van de Ven, Gray; Bergvall, Tonali; Savio, Gallagher, Kudus; Solanke
Coventry City: Rushworth; Dasilva, Pinnock, Thomas, van Ewijk; Yirenkyi, Grimes; Mason-Clark, Rudoni, Thomas-Asante; Awoniyi

Spurs are without Rodrigo Bentancur through suspension and Pedro Porro is confirmed out, along with Mikhail Mudryk, Wilson Odobert and Xavi Simons. Dejan Kulusevski and Andrew Robertson are both listed as questionable. Coventry have Kesler-Hayden doubtful at right back, while Amenda, Josh Eccles, Liam Woolfenden and Haji Wright are all confirmed out, trimming their options across the squad.

Tottenham are sizeable favourites on home turf and even with the absences, their predicted lineup carries plenty of quality. Savio and Mohammed Kudus offer pace and creativity in wide areas, while Dominic Solanke leads the line and is the standout anytime scorer option. Coventry's Tola Awoniyi leads a limited attacking line and will need everything to go right to cause an upset. Spurs on the moneyline is a straightforward parlay anchor, and the over on goals looks attractive given Tottenham's attacking depth versus Coventry's depleted defensive resources.

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