Premier League Gameweek 8 Predicted Lineups: Chelsea vs Tottenham Hotspur

Gameweek 8 arrives with a rash of significant absences reshaping several contenders. Arsenal head into their home fixture without Bukayo Saka and William Saliba, two of their most influential players, while Tottenham Hotspur travel to Stamford Bridge carrying doubts over four defenders including Andrew Robertson and Toby Adarabioyo. The depth of those injury lists will test both squads and open up interesting angles for bettors building parlays across the weekend.

Elsewhere, Aston Villa host Manchester City without Amadou Onana and Johan Manzambi, forcing a reshaped midfield, while Manchester United are missing a lengthy list of key personnel including Kobbie Mainoo, Benjamin Sesko and Marcus Rashford. Liverpool welcome Brighton and Hove Albion to Anfield with several doubts of their own to monitor, making this one of the more unpredictable Sundays of the early season.

Ipswich Town vs Nottingham Forest - Friday, 3:00 PM ET

Predicted Lineup Gameweek 8

Ipswich Town: Walton; Davis, O'Shea, Diop, Ouattara; Lukic, Palacios; Maeda, Enciso, Fatawu; Emersonn
Nottingham Forest: Sels; Milenkovic, Cunha, Murillo; Williams; Schlager, McAtee; Munoz; Ndoye, Gibbs-White; Delap

Ipswich Town are expected to line up in a 4-2-3-1 shape with Sasa Lukic listed as questionable alongside Eduardo Palacios, meaning the central midfield partnership is far from certain heading into Friday. Nottingham Forest have their own doubt in Morgan Gibbs-White, their creative hub in the attacking midfield role, while Igor Jesus and Nicolo Savona are both ruled out entirely. If Gibbs-White is unable to go, Forest's attacking threat could be considerably blunted.

For bettors, Forest arrive as moderate favorites on the moneyline given their generally stronger squad depth, but the question marks over Gibbs-White make the value calculation closer. With rain and strong winds forecast, a lower-scoring affair looks plausible, making the under an angle worth exploring. Both teams to score has appeal given Ipswich's attacking options across the front four, but Forest's defensive solidity without a fully fit forward line could suppress the home side. Liam Delap leading the line for Forest is a reliable first-goalscorer option.

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Aston Villa vs Manchester City - Saturday, 7:30 AM ET

Predicted Lineup Gameweek 8

Aston Villa: Suzuki; Mings, Lindelof, Torres, Cash; Kamara, Gomes; Buendia, McGinn; Jackson
Manchester City: Donnarumma; Gvardiol, Guehi, Dias, Nunes; Bouaddi, Anderson; Doku, Fernandez, Ndiaye; Haaland

Aston Villa are missing Johan Manzambi through injury, and his absence in the attacking midfield role leaves a notable gap. Amadou Onana is also out, leaving Boubacar Kamara and Joao Gomes to carry the midfield load. Manchester City have Matheus Nunes listed as questionable at right back, though he still appears in the predicted XI. Mateo Kovacic is a concern in midfield, and his absence would shift more creative responsibility onto Enzo Fernandez.

Manchester City are predicted as comfortable favorites here and Erling Haaland remains the obvious focal point of their attack regardless of personnel changes around him. Villa's defensive line of Victor Lindelof, Pau Torres and Tyrone Mings will face a stiff test against Doku and Haaland in particular. The City moneyline is the straightforward lean in this fixture. Haaland is always worth including in anytime goalscorer legs, and City's quality in transition through Doku makes both teams to score a reasonable secondary play if you trust Villa's attacking intent despite their absences.

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Arsenal vs Everton - Saturday, 10:00 AM ET

Predicted Lineup Gameweek 8

Arsenal: Raya; White, Konsa, Gabriel, Calafiori; Rice, Guimaraes; Madueke, Odegaard, Eze; Havertz
Everton: Pickford; Maitland-Niles, Branthwaite, Tarkowski, Mykolenko; Garner, Armstrong; Grealish, Dewsbury-Hall, Rohl; Barry

Arsenal are without Bukayo Saka and William Saliba, two of their most important players, yet still field a formidable predicted XI. Bruno Guimaraes partners Declan Rice in a deep midfield, with Eberechi Eze and Noni Madueke providing width. Ezri Konsa slots into central defence to cover for Saliba. Everton report no fresh injury concerns, giving them a clean bill of health, with Jack Grealish lining up on the left in what is expected to be an unfamiliar but energetic front unit.

Arsenal remain heavy favorites at home even without Saka, and the moneyline is hard to argue against for parlay builders looking for a reliable anchor. The total is an interesting debate: Arsenal's firepower through Havertz and the attacking midfield trio is significant, but Everton are structured and defensively minded. Havertz and Odegaard are the primary goalscorer options for Arsenal, while Grealish offers Everton their best creative outlet going forward. Both teams to score at a price could have value if Everton find a way to test Raya on the counter.

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Coventry City vs Fulham - Saturday, 10:00 AM ET

Predicted Lineup Gameweek 8

Coventry City: Rushworth; Dasilva, Pinnock, Thomas, van Ewijk; Yirenkyi, Grimes; Mason-Clark, Rudoni, Thomas-Asante; Awoniyi
Fulham: Leno; Robinson, Bassey, Affengruber, Castagne; Berge, Charles; Iwobi, King, Bobb; Garcia

Coventry City are missing four players including Haji Wright up front and Lee Woolfenden in defence, leaving them thin at both ends of the pitch. Tolu Awoniyi leads the line as a lone striker in a 4-2-3-1 setup. Fulham are without Ryan Sessegnon through suspension and have a doubt over Hugo Larsson in midfield, but their predicted lineup still carries quality through Alex Iwobi, Oscar Bobb and Gonzalo Garcia in the attacking positions. Shea Charles and Sander Berge form a solid base in midfield.

Fulham arrive as modest road favorites and their depth advantage over a depleted Coventry side is apparent. The Fulham moneyline or a draw-no-bet on Fulham could be a solid parlay component. Heavy rain and wind are forecast, which typically tightens up games at this level and makes the under worth considering. Gonzalo Garcia leads Fulham's goalscoring threat and is a name to consider in anytime scorer markets. Coventry will look to make it difficult at home, but their offensive losses make it hard to back them for more than one goal at best.

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Chelsea vs Tottenham Hotspur - Saturday, 12:30 PM ET

Predicted Lineup Gameweek 8

Chelsea: Penders; Acheampong, Colwill, Lacroix; Hato, Caicedo, Henderson, Neto; Palmer, Rogers; Pedro
Tottenham Hotspur: Kinsky; Robertson, van Hecke, van de Ven, Adarabioyo; Tonali, Gray; Marmoush, Maddison, Kudus; Solanke

This London derby is loaded with injury and suspension news on the Spurs side. Rodrigo Bentancur is suspended, Lucas Bergvall is out, and Savio, Destiny Udogie, Pedro Porro, Andrew Robertson and Toby Adarabioyo are all listed as either out or doubtful. Robertson and Adarabioyo appear in the predicted XI despite their doubts, which means late fitness checks are essential. Chelsea are without Reece James and Joao Gittens, with Malo Gusto also a doubt at right back, while Emiliano Martinez remains out in goal, leaving Mike Penders between the sticks.

Chelsea are narrow favorites at home and their superior depth in this fixture makes the home moneyline the natural lean. Cole Palmer remains the central creative figure for Chelsea and is a strong anytime goalscorer option. For Spurs, Dominic Solanke leads the attack, and Omar Marmoush provides flair on the left. With so many defensive doubts on the Spurs side, the over and both teams to score are angles worth exploring in this high-profile fixture. A depleted Spurs back line could be vulnerable to Chelsea's attacking fluidity through Palmer and Pedro Neto.

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Crystal Palace vs Newcastle United - Sunday, 10:00 AM ET

Predicted Lineup Gameweek 8

Crystal Palace: Benitez; Disasi, Richards, Canvot; Mitchell, Kamada, Wharton, Khalaili; Sarr, Pino; Strand Larsen
Newcastle United: Hornicek; Hall, Thiaw, Botman, Miley; Gonzalez, Joelinton; Barnes, Osula, Fernandez-Pardo; Wissa

Crystal Palace have a couple of notable absences with Chadi Riad and Takehiro Tomiyasu both out, while Ben Chilwell and Quentin Timber are doubtful. The predicted backline places Axel Disasi, Chris Richards and Canvot in a three-man defence. Newcastle are missing Vitor Livramento at right back and have doubts over Anthony Elanga and Jacob Ramsey in their attacking unit, with Will Osula expected to feature centrally alongside Yoane Wissa.

Newcastle arrive as slight road favorites, and their defensive structure anchored by Malick Thiaw and Sven Botman generally provides a solid base. The Magpies moneyline is a reasonable parlay piece. Palace have Ismaila Sarr and Yeremy Pino as their primary creative outlets, and Joelinton adds energy and physicality in Newcastle's midfield. Wissa leading the line for Newcastle gives them a physical aerial threat. The under is worth considering given both teams' defensive orientations, though Palace at home with a vocal crowd are capable of making this a competitive and entertaining contest.

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Hull City vs Brentford - Sunday, 10:00 AM ET

Predicted Lineup Gameweek 8

Hull City: Tzolakis; Giles, Egan, Ajayi, Herrington, Coyle; Thomas, Slater, Iroegbunam, Belloumi; McBurnie
Brentford: Kelleher; Lewis-Potter, van den Berg, Ajer, Kayode; Sangare, Jensen; Schade, Damsgaard, Anthony; Thiago

Hull City are without Matt Targett, Nobel Mendy, Eliot Matazo and Darko Gyabi among others, leaving them stretched across the squad. Their predicted 5-4-1 shape will likely prioritize defensive compactness. Brentford have their own concerns with Josh Dasilva and Amilcar Milambo both doubtful in midfield, and Vitaly Janelt and Yasin Yarmolyuk are suspended. Despite those absences, Brentford still field a strong predicted XI with Igor Thiago leading the line and Mikkel Damsgaard providing creativity.

Brentford are clear favorites here and their quality advantage is evident even with midfield suspensions. The Brentford moneyline is a solid parlay anchor. Igor Thiago is the standout anytime goalscorer option for the visitors, while Kevin Schade offers pace on the left to stretch Hull's backline. The over is worth a look given Brentford's attacking intent, though Hull's packed defensive setup could limit the goal flow. Caoimhin Kelleher starts in goal for Brentford after Jack Butland is ruled out for Hull, adding a narrative twist to the goalkeeping matchup.

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Liverpool vs Brighton and Hove Albion - Sunday, 10:00 AM ET

Predicted Lineup Gameweek 8

Liverpool: Alisson; Araujo, Jacquet, van Dijk, Kerkez; Gravenberch, Mac Allister; Barcola, Wirtz, Gakpo; Isak
Brighton and Hove Albion: Verbruggen; Kadioglu, Vuskovic, Dunk, Boscagli; Gross, Chema; De Cuyper, Ayari, Gomez; Kostoulas

Liverpool are without several key players including Dominik Szoboszlai, Jeremie Frimpong and Caoimhin Bradley, with Victor Munoz listed as doubtful. Despite that, the predicted XI remains formidable with Florian Wirtz operating centrally behind Alexander Isak. Brighton have a cluster of doubts in Kaoru Mitoma, Mats Wieffer and Yankuba Minteh among others, and their forward line is expected to feature the less experienced Kostoulas as the central striker, with Evan Ferguson ruled out.

Liverpool are slight underdogs here which, if accurate at kickoff, represents genuine value on the home side given the quality they can put out even with absences. Isak and Wirtz are the primary goalscorer options for Liverpool, while Florian Wirtz operating through the middle gives them a creative edge that Brighton's midfield may struggle to contain. Brighton's depleted attack makes the under an option, but Liverpool's forward quality tips the scales toward the over if they find their rhythm at Anfield. The Liverpool moneyline is worth anchoring a parlay around given the home advantage.

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Manchester United vs Bournemouth - Sunday, 10:00 AM ET

Predicted Lineup Gameweek 8

Manchester United: Lammers; Mazraoui, Maguire, Dalot; Santos, Baleba; Diallo, Tielemans, Fernandes; Mbeumo
AFC Bournemouth: Petrovic; Smith, Hill, Silva, Truffert; Adams, Christie; Rayan, Kluivert, Tavernier; Evanilson

Manchester United are significantly depleted with Kobbie Mainoo, Marcus Rashford, Benjamin Sesko, Manuel Ugarte, Luke Shaw and Lisandro Martinez all unavailable. The predicted lineup places Bruno Fernandes in a more advanced position alongside Youssouf Tielemans, with Bryan Mbeumo as the central forward. Bournemouth come in with Vitalie Milosavljevic and Emiliano Kroupi as doubts, and Julian Araujo and Alex Scott both ruled out, but their squad looks relatively settled with Justin Kluivert as the key creative force.

Bournemouth are genuine contenders in this fixture given United's lengthy injury list, and the away moneyline offers real value for parlay builders. Kluivert is an anytime goalscorer option worth considering, with his movement behind Evanilson a persistent threat. For United, Mbeumo leads the attack and will rely on service from Fernandes and Amad Diallo on the right. The total is a toss-up given United's defensive vulnerabilities with a makeshift backline, and both teams to score is a reasonable play given the attacking talent on both sides despite the absences.

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Sunderland vs Leeds United - Sunday, 12:30 PM ET

Predicted Lineup Gameweek 8

Sunderland: Roefs; Mukiele, Alderete, O'Nien, Reinildo; Xhaka, Sadiki; Hume, Diarra, Le Fee; Isidor
Leeds United: Trafford; Bogle, Justin, Elvedi, Muharemovic, Gudmundsson; Tanaka, Ampadu; Okafor, Stach; Calvert-Lewin

Sunderland are missing Kevin Danso through suspension and have Wia Isidor listed as doubtful despite appearing in the predicted lineup, along with doubts over Thomas Meunier and Daniel Ballard. Granit Xhaka is expected to anchor the midfield and provides calm and experience in an otherwise young squad. Leeds are without Joe Rodon and Mateo Joseph, and Daniel James is doubtful on the right, but Dominic Calvert-Lewin leads the attack with Noah Okafor and Anton Stach in support.

This Sunday closer is a genuinely open fixture with odds reflecting that uncertainty. Both teams have realistic paths to victory, and the draw market is priced attractively for those looking beyond win-lose outcomes. Calvert-Lewin is Leeds' most reliable goalscorer option given his aerial ability and movement in the box. For Sunderland, Enzo Le Fee and Habib Diarra carry the creative load, and if Isidor passes his fitness test, he adds genuine pace in behind. The match total is hard to call, but the competitive nature of this fixture lends itself to both teams to score as a parlay component.

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